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Post-conference Web site for the BISTI 2003 Symposium, "Digital Biology: The Emerging Paradigm"
 
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Biomedical Information Science and Technology Initiative (BISTI)
2003 Symposium


Digital Biology: The Emerging Paradigm

November 6-7, 2003
Natcher Conference Center
National Institutes of Health
Bethesda, Maryland

Sydney BrennerBiology Keynoter

Sydney Brenner, D. Phil.
Distinguished Professor
Salk Institue

According to the Lasker Foundation, which twice honored him: "Sydney Brenner likes beginnings.... While many scientists are gearing up to explore the new frontiers he has pioneered, Brenner's brain is already fidgeting and scouting around for a fresh path." Today, Dr. Brenner is moving beyond the genome as an inventory of function, to scout the world of integrated information in a quest to understand function in complex organisms. "We now have unprecedented ability to collect data about nature…" he says, "but there is now a crisis developing in biology, in that completely unstructured information does not enhance understanding."

"We need a framework to put all of this knowledge and data into — that is going to be the problem in biology," says Dr. Brenner in an interview with "Salk Signals" magazine. "We've reached the stage where we can't talk to each other — we've all become highly specialized. We need a framework, a framework where people can come back to us and say, 'Yes, I understand.' Driving toward that framework is really the big challenge, and I think that's what I'm going to do."

"There's nothing else as interesting as this," he says

.Acclaimed as one of the fathers of molecular biology, and a Nobel Laureate in Physiology or Medicine, Dr. Brenner is known for his brilliant creativity and trenchant wit. His accomplishments include seminal insights in identifying the existence and function of messenger RNA, and in deducing the triplet codon for coding proteins; launching c. elegans as a model organism for studying genetics, development, and complex physiological problems; advancing understanding of antibody diversity; promoting the concept of "biological containment" for recombinant DNA research; advocating and advancing the genome sequencing projects; spearheading the sequencing of the Japanese pufferfish to explore its compact genome; founding the multidisciplinary "Molecular Sciences Research Institute" to study biological function through the marriage of biology, computation and simulation; and developing a technology for "cloning" DNA on microbeads.

Born the son of a shoemaker in Germiston, South Africa in 1927, Dr. Brenner taught himself to read the newspaper at age 3, began studying chemistry books at age 6, and at age 14, won a scholarship to medical school at the University of Witwatersrand in Johannesburg. Dr. Brenner received his bachelors and masters degrees from the University of Witwatersrand, South Africa (1947 and 1951, respectively) and his D. Phil. in 1954 from Oxford University, England. In addition to a Nobel Prize and two Lasker awards, Dr. Brenner has been bestowed with numerous honors and awards. He also is a Fellow of King's College and the Royal Society. He has honorary memberships in numerous other societies and honorary degrees in over two dozen colleges and universities worldwide.

Nathan MyhrvoldTechnology Keynoter

Nathan Myhrvold, Ph.D.
Co-Founder and Managing Director, Intellectual Ventures


Dr. Nathan Myhrvold is cofounder and managing director of Intellectual Ventures, a private entrepreneurial firm started with former Microsoft colleague, Dr. Edward Jung. Before Intellectual Ventures, Dr. Myhrvold spent 14 years at Microsoft Corporation where he retired in May 2000 from his position as Chief Technology Officer.

At Intellectual Ventures, Dr. Myhrvold is focused on a variety of business interests relating to biotechnology, computer science, intellectual property and invention. Prior to his role as CTO of Microsoft, Dr. Myhrvold held various positions within the company and was responsible for founding Microsoft Research and numerous technology groups whose work resulted in many of Microsoft's core, leading products including Windows and Windows NT.

Before joining Microsoft in 1986, Dr. Myhrvold was founder and president of Dynamical Systems. Prior to that he was a postdoctoral fellow in the department of applied mathematics and theoretical physics at Cambridge University and worked with Professor Stephen Hawking on research in cosmology, quantum field theory in curved space time and quantum theories of gravitation.

Dr. Myhrvold holds a doctorate in theoretical and mathematical physics and a master's degree in mathematical economics from Princeton University. He also has a master's degree in geophysics and space physics and a bachelor's degree in mathematics, both from the UCLA. Dr. Myhrvold is an accomplished writer who has published scientific papers in several journals including Science, Nature, Paleobiology and the Physical Review. He co-authored The Road Ahead with Bill Gates and has contributed stories to many popular magazines including Fortune, Time, Talk Magazine, National Geographic Traveler and the online magazine, Slate

For general program questions, contact bistic@nih.gov.

Updated: 01/06/2004

 


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